Material Safety Data Sheet
     4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
 
Section 1 - Chemical Product and Company Identification
MSDS Name: 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
Catalog Numbers: 86-67333

Section 2 - Composition, Information on Ingredients 
CAS#1062368-24-4
Chemical Name: 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
Percent  95%
EINECS/ELINCS: Not available.
Hazard Symbols: Not available.
Risk Phrases: Not available.

Section 3 - Hazards Identification 
3.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
3.2 Label elements
This substance is not classified as dangerous according to Directive 67/548/EEC.
3.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Potential Health Effects
Eye: May cause eye irritation.
Skin: May be harmful if absorbed through skin. May cause skin irritation.
Ingestion: May be harmful if swallowed.
Inhalation: May be harmful if inhaled. May cause respiratory tract irritation.
Chronic: No information found.

Section 4 - First Aid Measures 
4.1 Description of first aid measures
If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact: Wash off with soap and plenty of water.
In case of eye contact: Flush eyes with water as a precaution.
If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

Section 5 - Fire Fighting Measures 
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available

Section 6 - Accidental Release Measures 
6.1 Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing vapours, mist or gas. For personal protection see section 8.
6.2 Environmental precautions
No special environmental precautions required.
6.3 Methods and materials for containment and cleaning up
Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.

Section 7 - Handling and Storage 
7.1 Precautions for safe handling
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature -20 °C

Store with desiccant.
Storage class (TRGS 510): Non Combustible Solids.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

Section 8 - Exposure Controls, Personal Protection 
Appropriate engineering controls
General industrial hygiene practice.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection
Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection is not required. Where protection from nuisance  levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
No special environmental precautions required.

Section 9 - Physical and Chemical Properties 
9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odour: No data available
c) Odour Threshold: No data available
d) pH: No data available
e) Melting point/freezing point: No data available
f) Initial boiling point and boiling range: No data available
g) Flash point: No data available
h) Evaporation rate: No data available
i) Flammability (solid, gas): No data available
j) Upper/lower flammability or explosive limits: No data available
k) Vapour pressure: No data available
l) Vapour density: No data available
m) Relative density: No data available
n) Water solubility: No data available
o) Partition coefficient: noctanol/water: No data available
p) Auto-ignition temperature: No data available
q) Decomposition temperature: No data available
r) Viscosity: No data available
s) Explosive properties: No data available
t) Oxidizing properties: No data available
9.2 Other safety information: No data available
 Molecular Formula: C24H25N5O
 Molecular Weight: 399.4882

Section 10 - Stability and Reactivity 
10.1 Reactivity: No data available
10.2 Chemical stability: Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions: No data available
10.4 Conditions to avoid: No data available
10.5 Incompatible materials: Strong oxidizing agents
10.6 Hazardous decomposition products: In the event of fire: see section 5

Section 11 - Toxicological Information 
11.1 Information on toxicological effects
Acute toxicity: No data available
Skin corrosion/irritation: No data available
Serious eye damage/eye irritation: No data available
Respiratory or skin sensitisation: No data available
Germ cell mutagenicity: No data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity: No data available
Specific target organ toxicity - single exposure: No data available
Specific target organ toxicity - repeated exposure: No data available
Aspiration hazard: No data available

Additional Information: RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

Section 12 - Ecological Information 
12.1 Toxicity: No data available
12.2 Persistence and degradability: No data available
12.3 Bioaccumulative potential: No data available
12.4 Mobility in soil: No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects: No data available

Section 13 - Disposal Considerations
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

Section 14 - Transport Information 
14.1 UN number
ADR/RID: -                     IMDG: -                                                  IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -                   IMDG: -                                                    IATA: -
14.4 Packaging group 
ADR/RID: -                   IMDG: -                                                     IATA: -
14.5 Environmental hazards
ADR/RID: no                IMDG Marine Pollutant: no                       IATA: no
14.6 Special precautions for user
no data available

Section 15 - Regulatory Information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
No data available
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities
 from the use of this product or information contained herein.