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Acebutolol

Material Safety Data Sheet
Acebutolol

Section 1 - Chemical Product and Company Identification
MSDS Name: Acebutolol
Catalog Numbers: 86-40558 

Section 2 - Composition, Information on Ingredients 
CAS#37517-30-9
Chemical Name: Acebutolol
Percent  99%min
EINECS/ELINCS: 253-539-0
Hazard Symbols: no information
Risk Phrases: Not available

Section 3 - Hazards Identification 
EMERGENCY OVERVIEW
Harmful if swallowed. May cause irritation to eyes, respiratory system and skin.

Potential Health Effects
Eye: May cause serious eye irritation. The toxicological properties of this material have not been fully investigated.
Skin: May cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation: Cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic: No information found.

Section 4 - First Aid Measures 
Eyes: If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.
Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
Inhalation: If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Notes to Physician: Treat symptomatically and supportively

Section 5 - Fire Fighting Measures 
General Information: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self contained breathing apparatus for fire fighting if necessary.

Section 6 - Accidental Release Measures 
Personal precautions, protective equipment and emergency procedures: Avoid dust formation. Avoid breathing vapors, mist or gas.
Environmental precautions: Do not let product enter drains.
 Methods and materials for containment and cleaning up: Sweep up and shovel. Keep in suitable, closed containers for disposal.
 Reference to other sections: For disposal see section 13

Section 7 - Handling and Storage 
Precautions for safe handling: Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
protection.
Conditions for safe storage, Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Section 8 - Exposure Controls, Personal Protection 
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.

Personal Protective Equipment
Eyes: Wear safety glasses and chemical goggles if splashing is possible.
Skin: Wear safety chemical goggles if splashing is possible.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions

Section 9 - Physical and Chemical Properties 
Physical State: White
Color: Powder
Odor: Not available
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available

Freezing/Melting Point: 119-123°C
Autoignition Temperature: Not available
Flash Point: Not available
Decomposition Temperature:Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C18H28N2O4
Molecular Weight: 336.43

Section 10 - Stability and Reactivity 
Chemical Stability: Stable. Incompatible with strong oxidizing agents, strong bases..
Conditions to Avoid: No decomposition if used and stored according to specifications..
Incompatibilities with Other Materials: Oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: has not been reported.

Section 11 - Toxicological Information 
RTECS#:
CAS#37517-30-9:  
LD50/LC50: RTECS:
Carcinogenicity:
Acebutolol ,99%min- Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other Studies: The toxicological properties have not been fully investigated.

Section 12 - Ecological Information 
Additional ecological information:
General notes: no data available

Section 13 - Disposal Considerations
Dispose of in a manner consistent  with federal, state, and local regulations.

Section 14 - Transport Information 
Shipping Name:
No data available

Section 15 - Regulatory Information
European/International Regulations
      European Labeling in Accordance with EC Directives
           Hazard Symbols: Not available
           Risk Phrases:
                   Not reported
           Safety Phrases:
                  Not reported
.
Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.