Material Safety Data Sheet
Methylcobalamin hydrate

Section 1 - Chemical Product and Company Identification
MSDS Name: Methylcobalamin hydrate
Catalog Numbers: 86-38748

Section 2 - Composition, Information on Ingredients 
CAS# 13422-55-4
Chemical Name: Methylcobalamin hydrate
Percent  98%
EINECS/ELINCS 236-535-3
Hazard Symbols: Xi
Risk Phrases: 36/37/38

Section 3 - Hazards Identification 
EMERGENCY OVERVIEW
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.

Potential Health Effects
Inhalation :May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion: May be harmful if swallowed.
Skin: May be harmful if absorbed through skin. May cause skin irritation.
Eyes: May cause eye irritation.

Section 4 - First Aid Measures 
If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact: Wash off with soap and plenty of water.
In case of eye contact: Flush eyes with water as a precaution.
If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water.

Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.

Section 5 - Fire Fighting Measures 
General Information: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide..

Section 6 - Accidental Release Measures 
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Section 7 - Handling and Storage 
7.1 Precautions for safe handling: Provide appropriate exhaust ventilation at places where dust is formed.
7.2 Conditions for safe storage, including any incompatibilities: Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature: -20 °C

Section 8 - Exposure Controls, Personal Protection 
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.

Personal Protective Equipment
Eyes: Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection:  Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of  protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respirators: Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Section 9 - Physical and Chemical Properties 
Physical State: Crystalline powder
Color: Dark red to red
Odor: Not available
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.

Boiling Point: Not available.
Freezing/Melting Point:
Autoignition Temperature: Not available
Flash Point: Not available.
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C63H91CoN13O14P
Molecular Weight: 1344.38

Section 10 - Stability and Reactivity 
Chemical Stability: no data available
Conditions to Avoid: no data available
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: no data available
Hazardous Polymerization: has not been reported.

Section 11 - Toxicological Information 
RTECS#:   
Acute toxicity
LD50 Oral - rat - > 5.000 mg/kg
Primary irritant effect
      On the skin: Irritant for skin and mucous membranes.
      On the eye: Irritant effect
      Sensitization: No sensitizing effect known.
      Additional toxicolofical information: To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
Carcinogenicity:
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Methylcobalamin)
Other Studies: The toxicological properties have not been fully investigated.

Section 12 - Ecological Information 
Additional ecological information:
     General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water bodies or sewage system. Do not allow material to be released to the environment without proper governmental permits.

Section 13 - Disposal Considerations
Recommendation: Consult state, local or national regulations for proper disposal. Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - Transport Information 
Shipping Name: 2-(HYDROXYMETHYL)PYRIDINE
UN Number: Not available
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
WGK Germany: 2

Section 15 - Regulatory Information 
European Labeling in Accordance with EC Directives
      Hazard Class:Xi
      Risk Phrases:
             R 36/37/38 Irritating to eyes, respiratory system and skin
      Safety Phrases:
             S 24/ 25 Avoid contact with skin and eyes
             S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
             S 36/37/39 Wear suitable protective clothing
Information about limitation of use: Employment restrictions concerning young persons must be observed. For use only by technically qualified individuals.

Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.