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N-Phthaloylglycine;Phthalimidoacetic acid

Material Safety Data Sheet
N-Phthaloylglycine;Phthalimidoacetic acid 

Section 1 - Chemical Product and Company Identification
MSDS Name: N-Phthaloylglycine;Phthalimidoacetic acid
Catalog Numbers: 86-36606

Section 2 - Composition, Information on Ingredients 
CAS# 4702-13-0
Chemical Name: N-Phthaloylglycine;Phthalimidoacetic acid 
Percent  98%
EINECS/ELINCS 225-177-3
Hazard Symbols: Xn
Risk Phrases: 22-36/37/38
 
Section 3 - Hazards Identification 
EMERGENCY OVERVIEW
Harmful if swallowed. Cause irritating to eyes, respiratory system and skin

Potential Health Effects
Eye: Cause serious eye irritation. The toxicological properties of this material have not been fully investigated.
Skin: Cause skin irritation. The toxicological properties of this material have not been fully investigated.
Ingestion: :May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation: Cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic: No information found.

Section 4 - First Aid Measures 
Eyes:Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively

Section 5 - Fire Fighting Measures 
General Information: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - Accidental Release Measures 
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Section 7 - Handling and Storage 
Handling: Keep containers tightly sealed. Store in cool, dry place in tightly closed containers. Ensure good ventilation/exhaustion at the workplace.
Information about protection against explosions and fires: Keep ignition sources away- Do not smoke.
Storage: Store away from water. Store away from oxidizing agents..
Further Information: This product is hygroscopic. Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Protect from humidity and keep away from water.

Section 8 - Exposure Controls, Personal Protection 
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.

Personal Protective Equipment
Eyes:Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU)..
Skin: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Clothing:  Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace..
Respirators: Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Section 9 - Physical and Chemical Properties 
Physical State:  microcrystalline powder
Color: off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.

Boiling Point: 454
Freezing/Melting Point: 193-196 °C(lit.)
Autoignition Temperature: Not available
Flash Point: Not available
Decomposition Temperature:Not available.
Solubility: Very soluble
Specific Gravity/Density: 1.45 g/cm3
Molecular Formula: C10H7NO4
Molecular Weight: 205.16

Section 10 - Stability and Reactivity 
Chemical Stability: Not avaialbe.
Conditions to Avoid: Incompatible materials, expore to air.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, oxides of phosphorus, carbon dioxide, phosphine..
Hazardous Polymerization: has not been reported.

Section 11 - Toxicological Information 
RTECS#:   
CAS# 4702-13-0:
Carcinogenicity: N-Phthaloylglycine;Phthalimidoacetic acid, 98% - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Other Studies: The toxicological properties have not been fully investigated.

Section 12 - Ecological Information 
Additional ecological information:
     General notes: Water hazard class 3

Section 13 - Disposal Considerations 
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - Transport Information 
Shipping Name: Lercanidipine mainring
UN Number: Not available
Packing Group: Not available

Section 15 - Regulatory Information 
European Labeling in Accordance with EC Directives
      Hazard Class:Not Available
      Risk Phrases:
             R 22 Harmful if swallowed
             R 36/37/38 Irritating to eyes, respiratory system and skin
      Safety Phrases:
             S 22 Do not brea the dust
             S 24/25 Avoid contact with skin and eyes
             S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
             S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection

Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.