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Furocemide

Material Safety Data Sheet
Furocemide
Section 1 - Chemical Product and Company Identification
MSDS Name: Furocemide
Catalog Numbers: 86-23519

Section 2 - Composition, Information on Ingredients 
CAS#54-31-9
Chemical Name: Furocemide
Percent  98%
EINECS/ELINCS:  200-203-6
Classification of the substance or mixture
According to Regulation (EC) No1272/2008
Reproductive toxicity (Category 1B)
According to European Directive 67/548/EEC as amended.
May cause harm to the unborn child.
Label elements
Pictogram 
Signal word: Danger
Hazard statement(s)
H360 May damage fertility or the unborn child.
Precautionary statement(s)
P201 Obtain special instructions before use.
P308 + P313 IF exposed or concerned: Get medical advice/attention.

Section 3 - Hazards Identification 
EMERGENCY OVERVIEW
Harmful if swallowed. Cause irritating to eyes, respiratory system and skin

Potential Health Effects
Inhalation: May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion: May be harmful if swallowed.
Skin: May be harmful if absorbed through skin. May cause skin irritation. 
Eyes: May cause eye irritation.

Section 4 - First Aid Measures 
General advices: Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled: If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed:Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Notes to Physician: Treat symptomatically and supportively

Section 5 - Fire Fighting Measures 
General Information: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - Accidental Release Measures 
Personal precautions: Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Evacuate personnel to safe areas.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Keep in suitable, closed containers for disposal.

Section 7 - Handling and Storage 
Precautions for safe handling: Avoid formation of dust and aerosols.Avoid exposure - obtain special instructions before use.
Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
Conditions for safe storage: Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Section 8 - Exposure Controls, Personal Protection 
Engineering Controls: Use adequate ventilation to keep airborne concentrations low.

Personal protective equipment
Respiratory protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and
components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection: The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Handle with gloves.
Eye protection: Safety glasses with side-shields conforming to EN166
Skin and body protection: Choose body protection according to the amount and concentration of the dangerous substance at the work place.

Hygiene measures: Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.

Section 9 - Physical and Chemical Properties 
Physical State: Powder
Color: White
Odor: Not available
pH: Not available.
Vapor Pressure: 101 hPa (76 mmHg) at 75 °C (167 °F).
Viscosity: Not available.
Boiling Point: 140 °C
Freezing/Melting Point: -59 °C
Autoignition Temperature: Not available
Flash Point: 17 °C (63 °F) - closed cup
Decomposition Temperature:Not available.
Solubility: Not available
Specific Gravity/Density: 0.815 g/mL at 25 °C(lit.)
Molecular Formula:C9H21BO3
Molecular Weight: 188.07

Section 10 - Stability and Reactivity 
Chemical stability: Stable under recommended storage conditions.  
Possibility of hazardous reactions: Vapours may form explosive mixture with air. 
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Strong oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Borane/boron oxides

Section 11 - Toxicological Information 
Acute toxicity
LD50 Oral - mouse - 2,500 mg/kg
Skin corrosion/irritation
Serious eye damage/eye irritation: Eyes - rabbit - Mild eye irritation
Respiratory or skin sensitization: no data available
Germ cell mutagenicity: no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH.
NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA.
Reproductive toxicity: no data available
Specific target organ toxicity - single exposure (GHS): no data available
Specific target organ toxicity - repeated exposure (GHS): no data available
Aspiration hazard: no data available 
Signs and Symptoms of Exposure: To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Additional Information:RTECS: ED5950000

Section 12 - Ecological Information 
Additional ecological information:
   General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water bodies or sewage system. Do not allow material to be released to the environment without proper governmental permits.

Section 13 - Disposal Considerations
Product: Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Observe all federal, state, and local environmental regulations. Contact a licensed professional waste disposal service to dispose of this material. 
Contaminated packaging: Dispose of as unused product.

Section 14 - Transport Information 
DOT (US)
UN-Number: 2616          Class: 3                    Packing group: II
Proper shipping name: Triisopropyl borate
Marine pollutant: No
Poison Inhalation Hazard: No
IMDG
UN-Number: 2616          Class: 3                    Packing group: II                     EMS-No: F-E, S-D
Proper shipping name: TRIISOPROPYL BORATE
Marine pollutant: No
IATA
UN-Number: 2616          Class: 3                    Packing group: II
Proper shipping name: Triisopropyl borate

Section 15 - Regulatory Information 
OSHA Hazards
Flammable liquid, Target Organ Effect

DSL Status
This product contains the following components listed on the Canadian NDSL list. All other components are on the Canadian DSL list.
Triisopropyl borate                         CAS-No. 5419-55-6
European Labeling in Accordance with EC Directives
      Hazard Class:F
      Risk Phrases:
             R 11 Highly Flammable
      Safety Phrases:
             S 9 Keep container in a well-ventilated place
             S 16 Keep away from sources of ignition - No smoking
             S 33 Take precautionary measures against static discharges
Information about limitation of use: Employment restrictions concerning young persons must be observed. For use only by technically qualified individuals.

Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.