Material Safety Data Sheet
4-Nitrophenylchloroformate
Section 1 - Chemical Product and Company Identification
MSDS Name: 4-Nitrophenylchloroformate
Catalog Numbers: 86-22814

Section 2 - Composition, Information on Ingredients 
CAS# 7693-46-1
Chemical Name: 4-Nitrophenylchloroformate
Percent  98%
EINECS/ELINCS 231-706-9
Hazard Symbols: C, Xi
Risk Phrases: 34-36/37

Section 3 - Hazards Identification 
3.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Skin corrosion (Category 1B)
Specific target organ toxicity - single exposure (Category 3)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Causes burns. Irritating to eyes and respiratory system.
3.2 Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram 
Signal word: Danger
Hazard statement(s)
H314 Causes severe skin burns and eye damage.
H335 May cause respiratory irritation.
Precautionary statement(s)
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/ physician.
Supplemental Hazard Statements: none
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)
R-phrase(s)
R34 Causes burns.
R36/37 Irritating to eyes and respiratory system.
S-phrase(s)
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
3.3 Other hazards: Lachrymator.

Section 4 - First Aid Measures 
4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact: Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a physician.
In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
4.3 Indication of any immediate medical attention and special treatment needed
no data available

Section 5 - Fire Fighting Measures 
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available

Section 6 - Accidental Release Measures 
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.

Section 7 - Handling and Storage 
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature: 2 - 8 °C
Handle and open container with care. Moisture sensitive.
7.3 Specific end use(s)
no data available

Section 8 - Exposure Controls, Personal Protection 
8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.  Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Section 9 - Physical and Chemical Properties 
Physical State: powder
Color: Off-white
Odor: Not available
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 159 - 162 °C at 25 hPa - lit.
Freezing/Melting Point: Melting point/range: 77 - 79 °C - lit
Autoignition Temperature: Not available
Flash Point: Not available
Decomposition Temperature:Not available.
Solubility: Not available
Specific Gravity/Density: Not determined
Molecular Formula: C7H4ClNO4
Molecular Weight: 201.56

Section 10 - Stability and Reactivity 
10.1 Reactivity: no data available
10.2 Chemical stability: no data available
10.3 Possibility of hazardous reactions: no data available
10.4 Conditions to avoid: no data available
10.5 Incompatible materials: acids, Strong bases
10.6 Hazardous decomposition products: Other decomposition products - no data available
 

Section 11 - Toxicological Information 

11.1 Information on toxicological effects
Acute toxicity: no data available
Skin corrosion/irritation: no data available
Serious eye damage/eye irritation: no data available
Respiratory or skin sensitization: no data available
Germ cell mutagenicity: no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity: no data available
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation.
Specific target organ toxicity - repeated exposure: no data available
Aspiration hazard: no data available
Potential health effects
Inhalation: May be harmful if inhaled. Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. Causes respiratory
tract irritation.
Ingestion: May be harmful if swallowed. Causes burns.
Skin: May be harmful if absorbed through skin. Causes skin burns.
Eyes: Causes eye burns.
Signs and Symptoms of Exposure
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea 

Section 12 - Ecological Information 
12.1 Toxicity: no data available
12.2 Persistence and degradability: no data available
12.3 Bioaccumulative potential: no data available
12.4 Mobility in soil: no data available
12.5 Results of PBT and vPvB assessment: no data available
12.6 Other adverse effects: no data available

Section 13 - Disposal Considerations
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

Section 14 - Transport Information 
14.1 UN number
ADR/RID: 3261                                      IMDG: 3261                                               IATA: 3261
14.2 UN proper shipping name
ADR/RID: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (4-Nitrophenyl chloroformate)
IMDG: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (4-Nitrophenyl chloroformate)
IATA: Corrosive solid, acidic, organic, n.o.s. (4-Nitrophenyl chloroformate)
14.3 Transport hazard class(es)
ADR/RID: 8                                             IMDG: 8                                                    IATA: 8
14.4 Packaging group
ADR/RID: II                                            IMDG: II                                                     IATA: II
14.5 Environmental hazards
ADR/RID: no                                          IMDG Marine Pollutant: no                        IATA: no
14.6 Special precautions for user
no data available

Section 15 - Regulatory Information 
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment
no data available

Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.