Material Safety Data Sheet
(TRIMETHYLSILYL)DIAZOMETHANE
Section 1 - Chemical Product and Company Identification
MSDS Name: (TRIMETHYLSILYL)DIAZOMETHANE
Catalog Numbers: SC-47478
Section 2 - Composition, Information on Ingredients
CAS#18107-18-1
Chemical Name: (TRIMETHYLSILYL)DIAZOMETHANE
Percent 2 M solution in Hexane
EINECS/ELINCS: Not available
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Harmful if swallowed. Causes eye irritation.Toxic if absorbed through skin. Causes skin irritation.
Potential Health Effects
Eye: Causes eye irritation.
Skin: Toxic if absorbed through skin. Causes skin irritation.
Ingestion: Harmful if swallowed. Toxic if swallowed. Aspiration hazard if swallowed. can enter lungs and cause damage.
Inhalation: Preliminary data indicates this product may be highly toxic or fatal ifinhaled. Inhalation may provoke the following symptoms: pulmonary edemaSymptoms may be delayed for hours after exposure. May be fatal ifinhaled. Causes respiratory tract irritation. Vapours may cause drowsinessand dizziness.
Chronic: Limited evidence of a carcinogenic effect.
Section 4 - First Aid Measures
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of soap and water.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Notes to Physician: Treat symptomatically and supportively
Section 5 - Fire Fighting Measures
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Do not let this chemical enter the environment.
Section 7 - Handling and Storage
Handling: Handle products containing trimethylsilyl diazomethane only in a closed system or effectively ventilatedlaboratory hood.Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes.Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostaticcharge.
Storage: Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which areopened must be carefully resealed and kept upright to prevent leakage.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment
Eyes: Face shield and safety glasses Use equipment for eye protection tested and approved underappropriate government standards such as NIOSH (US) or EN 166(EU).
Skin: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose ofcontaminated gloves after use in accordance with applicable laws and good laboratory practices.Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC andthe standard EN 374 derived from it.
Clothing: Complete suit protecting against chemicals, The type of protective equipment must be selectedaccording to the concentration and amount of the dangerous substance at the specific workplace.
Respirators:Where risk assessment shows air-purifying respirators are appropriate use a full-face respiratorwith multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backupto engineering controls. If the respirator is the sole means of protection, use a full-face supplied airrespirator.Use respirators and components tested and approved under appropriate governmentstandards such as NIOSH (US) or CEN (EU).
Section 9 - Physical and Chemical Properties
Physical State: liquid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure:Not available.
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Viscosity: Not available.
Freezing/Melting Point:Not available.
Autoignition Temperature: Not available
Flash Point: -26 °C - closed cup
Decomposition Temperature:Not available
Water Solubility: Not available
Specific Gravity/Density:0.773 g/mL at 25 °C
Molecular Formula: C4H10N2Si
Molecular Weight: 114.22
Section 10 - Stability and Reactivity
Chemical Stability: Not available
Conditions to Avoid: Incompatible materials.
Incompatible materials: Oxidizing agents, Incompatible with:, Chlorine, Fluorine, Perchlorates.
Hazardous Decomposition Products: Hazardous decomposition products - Trimethylsilyl diazomethane in alcoholic solvents under acidic orbasic conditions can lead to the formation of diazomethane.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
RTECS#:Not available
CAS#18107-18-1
LD50/LC50: RTECS:Not available
Carcinogenicity:
IARC:No component of this product present at levels greater than or equal to 0.1% is identified asprobable, possible or confirmed human carcinogen by IARC.
(TRIMETHYLSILYL)DIAZOMETHANE,2 M solution in Hexane- Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information found
Other Studies: The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information.
WGK Germany: 3
PackingGroup: II
Section 12 - Ecological Information
Additional ecological information:
General notes: no data available
Section 13 - Disposal Considerations
Waste treatment methods
Product: Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging:Dispose of as unused product.
Section 14 - Transport Information
14.1 UN number
ADR/RID: 3383 IMDG: 3383 IATA: 3383
14.2 UN proper shipping name
ADR/RID: TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S. (n-Hexane, (TRIMETHYLSILYL)DIAZOMETHANE)
IMDG: TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S. (n-Hexane,(TRIMETHYLSILYL)DIAZOMETHANE)
IATA: Toxic by inhalation liquid, flammable, n.o.s. (n-Hexane, (TRIMETHYLSILYL)DIAZOMETHANE)
Passenger Aircraft: Not permitted for transport
Cargo Aircraft: Not permitted for transport
14.3 Transport hazard class(es)
ADR/RID: 6.1 (3) IMDG: 6.1 (3) IATA: 6.1 (3)
14.4 Packaging group
ADR/RID: I IMDG: I IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
no data available
Section 15 - Regulatory Information
European Labeling in Accordance with EC Directives
Risk Phrases:
R12: Extremely Flammable
R19: May form explosive peroxides
R22: Harmful if swallowed
R66: Repeated exposure may cause skin dryness or cracking
R67: Vapors may cause drowsiness and dizziness
R65: Harmful: May cause lung damage if swallowed
R62: Possible risk of impaired fertility
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
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R48/20: Harmful: danger of serious damage to health by prolonged exposure through inhalation
R38: Irritating to the skin
R11: Highly Flammable
R23: Toxic by inhalation
Safety Phrases:
S9: Keep container in a well-ventilated place
S16: Keep away from sources of ignition - No smoking
S29: Do not empty into drains
S33:Take precautionary measures against static discharges
S36/37:Wear suitable protective clothing and gloves
S61: Avoid release to the environment. Refer to special instructions safety data sheet
S62: If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.
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