Material Safety Data Sheet

Zinc pyrithione

Section 1 - Chemical Product and Company Identification

MSDS Name: Zinc pyrithione

Catalog Numbers: SC-15992

Identified uses : Laboratory chemicals, Manufacture of substances

 

Section 2 - Composition, Information on Ingredients

CAS# 13463-41-7

Chemical Name: Zinc pyrithione

Percent  96%

EINECS/ELINCS: 236-671-3

Section 3 - Hazards Identification 

3.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008

Acute toxicity, Oral (Category 3), H301

Acute toxicity, Inhalation (Category 3), H331

Serious eye damage (Category 1), H318

Acute aquatic toxicity (Category 1), H400

Chronic aquatic toxicity (Category 1), H410

For the full text of the H-Statements mentioned in this Section, see Section 16.

Classification according to EU Directives 67/548/EEC or 1999/45/EC

T, N        Toxic, Dangerous for the environment            R22, R23, R41, R50/53

3.2 Label elements

Labelling according Regulation (EC) No 1272/2008

Pictogram          

Signal word             Danger

Hazard statement(s)

H301 + H331     Toxic if swallowed or if inhaled

H318            Causes serious eye damage.

H410           Very toxic to aquatic life with long lasting effects.

Precautionary statement(s)                

P261    Avoid breathing dust.

P273    Avoid release to the environment.

P280    Wear protective gloves/ eye protection/ face protection.

P301 + P310   IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.

P305 + P351 + P338  IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P311             Call a POISON CENTER or doctor/ physician.

Supplemental Hazard Statements          none

3.3 Other hazards - none

 

Section 4 - First Aid Measures 

4.1 Description of first aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.  

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact.

Wash off with soap and plenty of water. Consult a physician.   

In case of eye contact

Flush eyes with water as a precaution.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.   

 

Section 5 - Fire Fighting Measures 

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture

Carbon oxides, Nitrogen oxides (NOx), Sulphur oxides, Zinc/zinc oxides

5.3 Advice for firefighters

Wear self contained breathing apparatus for fire fighting if necessary.

5.4 Further information

No data available 

 

Section 6 - Accidental Release Measures 

6.1 Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.

For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.  

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

6.4 Reference to other sections

For disposal see section 13. 

 

Section 7 - Handling and Storage 

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.

Provide appropriate exhaust ventilation at places where dust is formed.  

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

 

Section 8 - Exposure Controls, Personal Protection 

8.1 Control parameters

Components with workplace control parameters

8.2 Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).  

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.  

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

 

Section 9 - Physical and Chemical Properties 

Physical State: Powder.

Color: Off-White

Odor: Not available

pH: Not available

Vapor Pressure: Not available.   

Viscosity: Not available.

Boiling Point: Not available.

Freezing/Melting Point: Not available.  

Autoignition Temperature: Not available

Flash Point: Not available.

Decomposition Temperature:Not available.

Solubility: Not available

Specific Gravity/Density: Not available.

Molecular Formula: C10H8N2O2S2Zn

Molecular Weight: 317.7

 

Section 10 - Stability and Reactivity 

10.1 Reactivity: No data available

10.2 Chemical stability: Stable under recommended storage conditions.  

10.3 Possibility of hazardous reactions: No data available

10.4 Conditions to avoid: Light.  

10.5 Incompatible materials: Oxidizing agents, Heavy metals, Reducing agents

10.6 Hazardous decomposition products

Other decomposition products - No data available

 

Section 11 - Toxicological Information 

11.1 Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - male and female - 269 mg/kg

(OECD Test Guideline 401)

LC50 Inhalation - Rat - male - 4 h - 0,84 mg/l

(OECD Test Guideline 403)

LD50 Dermal - Rabbit - male and female - > 2.000 mg/kg

Skin corrosion/irritation

Skin - Rabbit

Result: No skin irritation - 4 h

(OECD Test Guideline 404)

Serious eye damage/eye irritation

Eyes - Rabbit

Result: Risk of serious damage to eyes. - 24 h

(OECD Test Guideline 405)  

Respiratory or skin sensitization

Maximisation Test (GPMT) - Guinea pig

Result: Does not cause skin sensitisation.

(OECD Test Guideline 406)

Germ cell mutagenicity

Ames test

S. typhimurium

Result: negative  

Carcinogenicity

IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity

Reproductive toxicity - Rabbit - Oral

Effects on Fertility: Post-implantation mortality (e.g., dead and/or resorbed implants per total number of

implants). Effects on Embryo or Fetus: Fetal death.

Reproductive toxicity - Rat - Skin

Effects on Newborn: Weaning or lactation index (e.g., # alive at weaning per # alive at day 4).

Developmental Toxicity - Rabbit - Skin

Effects on Embryo or Fetus: Fetal death.

Developmental Toxicity - Rat - Oral

Effects on Embryo or Fetus: Fetotoxicity (except death, e.g., stunted fetus). Specific Developmental

Abnormalities: Musculoskeletal system

Specific target organ toxicity - single exposure

no data available

Specific target organ toxicity - repeated exposure

no data available

Aspiration hazard

no data available

Potential health effects

Inhalation              May be harmful if inhaled. Causes respiratory tract irritation.

Ingestion               Harmful if swallowed.

Skin                   May be harmful if absorbed through skin. Causes skin irritation.

Eyes                  Causes eye burns.

Signs and Symptoms of Exposure

To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

Additional Information

Repeated dose toxicity - Rat - male and female - Oral - No observed adverse effect level - 0,5 mg/kg

RTECS: ZH0950000  

Section 12 - Ecological Information 

12.1 Toxicity

Toxicity to fish                             flow-through test LC50 - Pimephales promelas (fathead minnow) - 0,0026 mg/l - 96 h

Toxicity to daphnia and other aquatic invertebrates    flow-through test EC50 - Daphnia magna (Water flea) - 0,008 mg/l - 48 h

Toxicity to bacteria            Respiration inhibition EC50 - Sludge Treatment - 2,4 mg/l - 3 h (OECD Test Guideline 209)

12.2 Persistence and degradability

Biodegradability           aerobic - Exposure time 28 d

Result: 39 % - Not readily biodegradable.

                         (OECD Test Guideline 301B)

12.3 Bioaccumulative potential

Bioaccumulation              Cyprinus carpio (Carp) - 56 d

Bioconcentration factor (BCF): < 50

                            (OECD Test Guideline 305C)

Remarks: Does not bioaccumulate.

12.4 Mobility in soil

no data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted  

12.6 Other adverse effects

Very toxic to aquatic life with long lasting effects.

 

Section 13 - Disposal Considerations

13.1 Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material.

Contaminated packaging

Dispose of as unused product. 

 

Section 14 - Transport Information 

14.1 UN number

ADR/RID: 2811          IMDG: 2811                      IATA: 2811  

14.2 UN proper shipping name

ADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (Pyrithione zinc)

IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Pyrithione zinc)

IATA: Toxic solid, organic, n.o.s. (Pyrithione zinc)

14.3 Transport hazard class(es)

ADR/RID: 6.1         IMDG: 6.1                      IATA: 6.1  

14.4 Packaging group

ADR/RID: II          IMDG: II                        IATA: II

14.5 Environmental hazards

ADR/RID: yes       IMDG Marine pollutant: yes       IATA: no

14.6 Special precautions for user

no data available

Section 15 - Regulatory Information

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

no data available

15.2 Chemical Safety Assessment

no data available

 

Section 16 - Additional Information

Full text of H-Statements referred to under sections 2 and 3.

Acute Tox.               Acute toxicity

Aquatic Acute            Acute aquatic toxicity

Aquatic Chronic          Chronic aquatic toxicity

Eye Dam.                Serious eye damage

H301                    Toxic if swallowed.

H301 + H331             Toxic if swallowed or if inhaled

H318                   Causes serious eye damage.

H331                   Toxic if inhaled.

Full text of R-phrases referred to under sections 2 and 3

N                      Dangerous for the environment

T                      Toxic

R22                   Harmful if swallowed.

R23                   Toxic by inhalation.

R41                   Risk of serious damage to eyes.

R50/53                Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment

 

While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.