Material Safety Data Sheet
Clindamycine phosphate 
 

Section 1 - Chemical Product and Company Identification
MSDS Name: Clindamycine phosphate 
Catalog Numbers: 86-37576

Section 2 - Composition, Information on Ingredients 
CAS#24729-96-2
Chemical Name: Clindamycine phosphate
Percent  97%min
EINECS/ELINCS: 246-433-0

Section 3 - Hazards Identification 
3.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Acute toxicity, Oral (Category 4)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Harmful if swallowed. 
3.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram                           
Signal word                       Warning
Hazard statement(s)
H302                                 Harmful if swallowed.
Precautionary statement(s)                  none
Supplemental Hazard Statements       none
According to European Directive 67/548/EEC as amended.
 Hazard symbol(s)           R-phrase(s)
R22                                 Harmful if swallowed.
S-phrase(s)
S36                                Wear suitable protective clothing.  3.3 Other hazards - none

Section 4 - First Aid Measures
4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician. 
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 
4.2 Most important symptoms and effects, both acute and delayed
Gastrointestinal disturbance, Vomiting, Diarrhoea 
4.3 Indication of any immediate medical attention and special treatment needed
no data available

Section 5 - Fire Fighting Measures 
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), Sulphur oxides, Oxides of phosphorus, Hydrogen chloride gas 
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available.

Section 6 - Accidental Release Measures 
6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas. For personal protection see section 8. 
6.2 Environmental precautions
Do not let product enter drains. 
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. 
6.4 Reference to other sections
For disposal see section 13. 
Section 7 - Handling and Storage 
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.  
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas.
7.3 Specific end uses
no data available 
Section 8 - Exposure Controls, Personal Protection 
Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.

Personal Protective Equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. 
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). 
Section 9 - Physical and Chemical Properties 
Physical State: Solid .
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Melting point: Not available..
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits: Not available.
Explosion Limits: Not available.
Decomposition Temperature: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C18H34ClN2O8PS.
Molecular Weight: 504.97.

Section 10 - Stability and Reactivity 
10.1 Reactivity
no data available
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available 
10.5 Incompatible materials
Aminophylline, ampicillin sodium, barbiturates, calcium gluconate, magnesium sulfate, phenytoin, sodium vitamins of the B group  
10.6 Hazardous decomposition products
Other decomposition products - no data available

Section 11 - Toxicological Information
11.1 Information on toxicological effects

Acute toxicity
LD50 Oral - rat - 1.832 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity)
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available 
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation                     May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion                      Harmful if swallowed.
Skin                              May be harmful if absorbed through skin. May cause skin irritation.
Eyes                             May cause eye irritation.
Signs and Symptoms of Exposure
Gastrointestinal disturbance, Vomiting, Diarrhoea 
Additional Information
RTECS: GF2625000 
Section 12 - Ecological Information 
12.1 Toxicity
no data available 
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
no data available
12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
no data available
12.6 Other adverse effects
no data available.

Section 13 - Disposal Considerations
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. 
Contaminated packaging
Dispose of as unused product.

Section 14 - Transport Information 
14.1 UN number
ADR/RID: -   IMDG: -    IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -                                    IMDG: -                                              IATA: -
14.4 Packaging group
ADR/RID: -                                   IMDG: -                                               IATA: -
14.5 Environmental hazards
ADR/RID: no                                IMDG Marine pollutant: no                  IATA: no
14.6 Special precautions for user
no data available 
Section 15 - Regulatory Information 
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
15.2 Chemical Safety Assessment

no data available       
Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.