Material Safety Data Sheet
Dolasetron
Section 1 - Chemical Product and Company Identification
MSDS Name: Dolasetron
Catalog Numbers: SC-25659

Section 2 - Composition, Information on Ingredients 
CAS#115956-12-2
Chemical Name: Dolasetron
Percent: 98%min
EINECS/ELINCS: N/A

Section 3 - Hazards Identification 
This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200).
Classification
Acute toxicity - Oral Category 4
Label elements
Signal word Warning
Hazard statements Symbols/Pictograms:  HARMFUL IF SWALLOWED  
Precautionary Statements - Prevention: Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product
Precautionary Statements - Response: IF exposed or concerned: Get medical advice/attention
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth
Precautionary Statements - Disposal:  Dispose of contents/container to an approved waste disposal plant
Hazards not otherwise classified (HNOC)
Hazards not otherwise classified (HNOC): Not applicable

Section 4 - First Aid Measures 
First Aid Measures: General advice Consult a physician if necessary. Remove to fresh air.
Eye contact: Wash with plenty of water.
Skin Contact: Wash skin with soap and water.
Inhalation: Remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration.
Ingestion: Never give anything by mouth to an unconscious person. Clean mouth with water.
Most important symptoms and effects, both acute and delayed
Symptoms: No information available.
Indication of any immediate medical attention and special treatment needed
Note to physicians Treat symptomatically.

Section 5 - Fire Fighting Measures 
Suitable extinguishing media: Dry chemical, foam, water spray, carbon dioxide.
Specific hazards arising from the chemical: Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so.
Special protective
equipment for firefighters: When extinguishing fire, be sure to wear personal protective equipment.

Section 6 - Accidental Release Measures 
Personal precautions, protective equipment and emergency procedures:
Use extra personal protective equipment (P3 filter respirator for toxic particles). Keep people away from and upwind of spill/leak. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and material for containment and cleaning up
Methods for containment: Prevent further leakage or spillage if safe to do so.
Methods for cleaning up: Use personal protective equipment as required. Cover powder spill with plastic sheet or tarp to minimize spreading and keep powder dry. Take up mechanically, placing in appropriate containers for disposal. Avoid creating dust. Clean contaminated surface thoroughly.

Section 7 - Handling and Storage 
Precautions for safe handling
Advice on safe handling Handle in accordance with good industrial hygiene and safety practice.
Conditions for safe storage, including any incompatibilities
Storage Conditions: Keep containers tightly closed in a dry, cool and well-ventilated place. Store at room temperature.
Incompatible materials: None known based on information supplied.

Section 8 - Exposure Controls, Personal Protection 
Control parameters
Exposure Guidelines: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.
Appropriate engineering controls
Engineering Controls: Showers
                      Eyewash stations
                      Ventilation systems
Individual protection measures, such as personal protective equipment
Eye/face protection: Wear safety glasses with side shields (or goggles).
Skin and Body Protection: Wear protective gloves and protective clothing.
Respiratory protection: If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene: Considerations Handle in accordance with good industrial hygiene and safety practice.

Section 9 - Physical and Chemical Properties 
Physical State: Solid
Color:
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available
Viscosity: Not available.
Boiling Point: 535.1 °C
Freezing/Melting Point: 278 °C
Autoignition Temperature: Not available
Flash Point: 277.4 °C
Decomposition Temperature: Not available
Solubility(ies):
[Water] No data available
[Other solvents] Soluble: Methanol
Specific Gravity/Density: 1.37 g/cm3
Molecular Formula: C19H20N2O3
Molecular Weight: 325.38

Section 10 - Stability and Reactivity 
Chemical stability: Stable under recommended storage conditions.
Possibility of Hazardous: Reactions None under normal processing.
Hazardous polymerization: No information available.
Conditions to avoid: Extremes of temperature and direct sunlight.
Incompatible materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon oxides. Nitrogen oxides (NOx).

Section 11 - Toxicological Information 
Information on likely routes of exposure
Inhalation: No data available.
Eye contact: No data available.
Skin Contact: No data available.
Ingestion: No data available.
Information on toxicological effects
Symptoms: No information available.
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Chronic Toxicity: No information available.
Numerical measures of toxicity - Product Information
Unknown acute toxicity No information available
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral) 500 mg/kg
 
Section 12 - Ecological Information 
Ecotoxicity: May cause long lasting harmful effects to aquatic life
100% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
Persistence and degradability: No information available.
Bioaccumulation: No information available.
Mobility: No information available.

Section 13 - Disposal Considerations 
Disposal of wastes: Disposal should be in accordance with applicable regional, national and local laws and regulations.
Contaminated packaging: Do not reuse container.

Section 14 - Transport Information 
DOT: Not regulated
IMDG: Not regulated
IATA : Not regulated

Section 15 - Regulatory Information 
US Federal Regulations
SARA 313: Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any
chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories
Acute health hazard: No
Chronic Health Hazard: No
Fire hazard: No
Sudden release of pressure hazard: No
Reactive hazard: No
CWA (Clean Water Act)
This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42).
US State Regulations
California Proposition 65
This product does not contain any Proposition 65 chemicals.
U.S. State Right-to-Know Regulations
This product does not contain any substances regulated by state right-to-know regulations

Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.