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Desoximetasone

Material Safety Data Sheet
Desoximetasone
Section 1 - Chemical Product and Company Identification
MSDS Name: Desoximetasone
Catalog Numbers: 86-36864

Section 2 - Composition, Information on Ingredients 
CAS#382-67-2
Chemical Name: Desoximetasone
Percent  95%min
EINECS/ELINCS: 206-845-3
Hazard Codes:Xn
Risk Phrases: 20/21/22-36/37/38-40-43

Section 3 - Hazards Identification 
EMERGENCY OVERVIEW
Harmful if swallowed. Irritate to eyes, respiratory system and skin.

Potential Health Effects
Eye: Cause eye irritation.
Skin: Cause skin irritation. May be harmful if absorbed through the skin. May cause sensitization by skin contact.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation: May cause respiratory tract irritation. May be harmful if inhaled.
Chronic: Limited evidence of a carcinogenic effect. 

Section 4 - First Aid Measures 
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of soap and water.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively

Section 5 - Fire Fighting Measures 
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - Accidental Release Measures 
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Do not let this chemical enter the environment.

Section 7 - Handling and Storage 
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Refrigerator

Section 8 - Exposure Controls, Personal Protection 
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.

Personal Protective Equipment
Eyes: Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact  with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Clothing: Wear appropriate protective gloves, clothing and goggles.
Body Protection:Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace
Respirators: Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as
NIOSH (US) or CEN (EU).

Section 9 - Physical and Chemical Properties 
Physical State: crystalline powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available
Viscosity: Not available.
Boiling Point: 532.251°Cat760mmHg

Freezing/Melting Point: 213-215°C
Autoignition Temperature: Not available
Flash Point: 275.696°C
Decomposition Temperature:Not available
Water Solubility: Not available
Specific Gravity/Density:1.259g/cm3
Molecular Formula: C22H29FO4
Molecular Weight:376.46

Section 10 - Stability and Reactivity 
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information 
RTECS#: TU3834000
CAS# 382-67-2:
LD50/LC50: RTECS:TU3834000
CAS#382-67-2:
Carcinogenicity:
Desoximetasone ,95%min - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information found
Other Studies: The toxicological properties have not been fully investigated. See actual entry in RTECS for complete information.

Section 12 - Ecological Information 
a health hazard

Section 13 - Disposal Considerations 
Dispose of in a manner consistent with federal, state, and local regulations.
WGK Germany : 3

Section 14 - Transport Information 
Shipping Name: not regular

Section 15 - Regulatory Information 
European Labeling in Accordance with EC Directives
      Hazard Class: Xn
        Risk Phrases:
            R620/21/22: Harmful by inhalation, in contact with skin and if swallowed
            R36/37/38: Irritating to eyes, respiratory system and skin
            R40: Limited evidence of a carcinogenic effect
            R43: May cause sensitization by skin contact
       Safety Phrases:
            S22: Do not breathe dust          
            S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
            S36: Wear suitable protective clothing   

Section 16 - Additional Information
While the information herein is believed to be reliable, it is furnished without warranty of any kind. It shall be used only as a guide. We assume no liabilities from the use of this product or information contained herein.