Acebutolol_CERTIFICATE OF ANALYSIS_DOCUMENTS & REFERENCE_Labseeker-Find chemicals, pharmaceuticals for your lab.

Certification of Analysis

Items of analysis		Specification	Results
Appearance		White or almost white, crystalline powder	White crystalline powder
Solubility		Freely soluble in water and in ethanol (96 percent), very slightly soluble in acetone and in methylene chloride.	Conforms
MP		About 143℃	143.8℃
Identification IR		Infrared absorption spectrophotometry (2.2.24). Preparation Discs. Comparisonacebutolol hydrochloride CRS.	Conforms
Identification chlorides		It gives reaction (a) of chlorides.	Conforms
PH		5.0-7.0	5.5
Loss on drying		≤0.5%	0.04%
Sulfated Ash		≤0.1%	0.05%
Heavy metals		≤10ppm	Conforms
Related Substances	Impurity B	≤0.2%	0.00%
	Impurity C	≤0.1%	0.04%
	Impurity I	≤0.2%	0.00%
Maximum Single Impurity		≤0.1%	0.06%
Total impurities		≤0.5%	0.18%
Assay(dried basis)		99.0%~101.0%	99.9%
Remark		Declaration: For laboratory use by technically qualified individual only
Conclusion		It accords with the Enterprise Standard

Analyst: Jack Fu Check: Anne Zhang Date: 2012-12-31